Potentially Groundbreaking Alzheimer's Study: Liver, Not Brain Source of Plaque?

Alzheimer's disease has perplexed scientists and researchers for years due to its complex and debilitatitng nature.  Not only is it difficult to diagnose, but symptoms of the disease are similar of many other forms of dementia.  A new study suggests the liver -- not the brain -- may be the organ for medical professionals to focus upon.

Read this excerpt from the article physorg.com, here:  

"Unexpected results . . . could completely alter scientists' ideas about Alzheimer's disease—pointing to the liver instead of the brain as the source of the "amyloid" that deposits as brain plaques associated with this devastating condition. The findings could offer a relatively simple approach for Alzheimer's prevention and treatment."

For more on Alzheimer's Disease, see our recent blog post here; we discuss the unlikely cast of characters uniting to fight the disease.  Evan H. Farr on Google +

Good cholesterol linked to reduced Alzheimer’s risk

Alzheimer’s disease is the 7^th leading cause of death and costs about 172 billion dollars annually.[1] Due to the disease’s debilitating nature, more than 10 million caregivers of individuals with the disease are unpaid family members, friends, or volunteers. For these reasons, it is no surprise that research and medical trials are ongoing to combat the disease. Just as important as research from the scientific community, is knowledge of the steps people can take to reduce their risk for developing the disease. The December issue of Archives of Neurology reported that a high level of “good” cholesterol has been found to be linked to a reduced risk for developing Alzheimer’s.[2]

Senior Journal reported on the study from the Archives, explaining that researchers studied 1,130 healthy adults from a pool of Medicare recipients from New York, to study a possible relationship between HDL and Alzheimer’s symptoms.

While the researchers conclude that higher HDL cholesterol was associated with a lowered risk of developing Alzheimer’s disease, they also note that “[a]n important consideration in the interpretation of the results is that it was conducted an urban multiethnic elderly community with a high prevalence of risk factors for mortality and dementia.” In other words, as applied to younger individuals, the correlation between HDL and reduced risk for developing Alzheimer’s is unclear.

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[1] Alz.org, Alzheimer’s Facts and Figures (2010), available at http://www.alz.org/alzheimers_disease_facts_and_figures.asp

[2] Senior Journal notes that the study was supported by the National Institute on Aging, the Charles S. Robertson Memorial Gift for Research in Alzheimer’s Disease and the Blanchette Hooker Rockefeller Foundation.

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