Showing posts with label alzheimer's disease. Show all posts
Showing posts with label alzheimer's disease. Show all posts

Monday, March 14, 2011

Potentially Groundbreaking Alzheimer's Study: Liver, Not Brain Source of Plaque?

Alzheimer's disease has perplexed scientists and researchers for years due to its complex and debilitatitng nature.  Not only is it difficult to diagnose, but symptoms of the disease are similar of many other forms of dementia.  A new study suggests the liver -- not the brain -- may be the organ for medical professionals to focus upon.

Read this excerpt from the article physorg.com, here:  
"Unexpected results . . . could completely alter scientists' ideas about Alzheimer's disease—pointing to the liver instead of the brain as the source of the "amyloid" that deposits as brain plaques associated with this devastating condition. The findings could offer a relatively simple approach for Alzheimer's prevention and treatment."
For more on Alzheimer's Disease, see our recent blog post here; we discuss the unlikely cast of characters uniting to fight the disease. 

Monday, March 7, 2011

"Largest Legislative Victory in Years" for Alzheimer Cause

The National Alzheimer’s Project Act (NAPA) is being touted as the “largest legislative victory in many years for the Alzheimer cause.” 
The Alzheimer’s Association persisted in its battle to pass the critical legislation. Congress unanimously approved the legislation, and President Obama has signed off.  According to this celebratory article, the victory was the result of a concerted effort by many individuals orginizations, and reportedly included about 50,000 emails, 10,000 telephone calls, and 1,000 meetings!

Once NAPA is in full-swing, our nation will have what Health and Human Services Secretary Kathleen Sebelius refers to as an “aggressive and coordinated national strategy” to combat the Alzheimer’s Disease crisis.

To celebrate this legislation, we've consolidated some of our most popular articles over the years on the Alzheimer cause. 

Excerpt: "[D]espite the disease’s prevalence, there are already two positive developments in 2011.  First, researchers seem excited about a new means to predict — and perhaps one day to diagnose — the disease with certainty in the living.  Second, an unlikely team of players  has unified on the front lines…"
 
Excerpt: "This grant funding to Virginia’s Medicaid system comes with high hopes and great expectations. The over $2 million in funding will be used to bolster services for two key underprivileged groups – the elderly and the disabled . . . [one such service is] in-home support services for sufferers of Alzheimer’s disease."

Excerpt: "Although most of the conditions on the revised list are rare, of tremendous importance for the aging population is the fact that the SSA has now included Early-Onset Alzheimer’s Disease, Mixed Dementia, and Primary Progressive Aphasia among the new fast-track conditions, meaning that people who are diagnosed with any of these conditions can now receive disability benefits very quickly."

Excerpt: "'[The use of] biomarkers to identify elderly persons at risk of developing dementia could be useful for early prevention, if and when such interventions are available, and treatment,' the author of the study explained."

Image Credit: Photographer: renjith krishnan


Friday, January 28, 2011

Who was supposed to be watching Grandma?

There is a popular tune you may have over the last couple of months called “Grandma Got Run Over by A Reindeer” which relates that Grandma -- after drinking too much eggnog -- went out into the winter cold to get her medication and was run over by a reindeer. The question is, “Who was supposed to be watching Grandma?”

Though this little tune is just for fun, it may very well raise alarms to many caregivers of the elderly. Caregivers know that even at a holiday party they cannot let down their diligent watch over their elderly loved one. As far-fetched as it may sound, with all the people and noise, an elderly family member with dementia or Alzheimer’s may be enjoying the family gathering and then suddenly become confused and walk to the door and leave.

For people with loved ones showing early signs of Alzheimer's, disability benefits may be easier to obtain than years past. VirginiaElderLaw.com reported early last year on the Social Security Administration's additions to the Compassionate Allowances list:
Last year, the SSA has added an additional 38 conditions to the Compassionate Allowances list, greatly expanding the number of people who are eligible for the Compassionate Allowances program.  Although most of the conditions on the revised list are rare, of tremendous importance for the aging population is the fact that the SSA has now included Early-Onset Alzheimer’s Disease, Mixed Dementia, and Primary Progressive Aphasia among the new fast-track conditions, meaning that people who are diagnosed with any of these conditions can now receive disability benefits very quickly.
For family caregivers the added stress of the holidays with decorating, shopping, parties and keeping up with all the family traditions is an overwhelming quest. Feelings of isolation, depression and sadness come with this added stress. There are millions of Americans who are caring for elderly frail loved ones and most of these caregivers will go through some of these emotions, especially this time of year.

There are some things you can do as a caregiver to help you and those you care for enjoy the holiday season:

Take care of yourself. Try to eat right, get plenty of sleep and exercise. This will help reduce stress and strengthen your ability to cope with caregiving responsibilities.

Prioritize your responsibilities. Perhaps instead of cooking a large family dinner, have everyone bring his or her favorite dish. Use paper plates. Forfeit the traditional outside light decorating for a lighted wreath on the front door. Choose one or two parties or concerts to attend instead of trying to do it all.

Arrange for help. Call on other family members to help with the caregiving while you do your shopping or go out for the evening. If family is not available, ask your church group or a neighbor if they would donate a few hours.

Use community services. Many senior centers provide meals for the elderly and supervised activities, on-site, at no charge or a minimal charge. For locating senior services in your state, call your state Area Agency on Aging or check the national website at http://www.n4a.org/

Use adult day care services. Some assisted living facilities provide day activities and meals for seniors on a day by day basis. Other organizations called "adult day service providers" specialize exclusively in this sort of care support at a reasonable cost. These support services provide respite for caregivers from their caregiving responsibilities as well as social interaction for their elderly family members. There is a cost for adult day services, but the benefit for all is worth it.
For example:
Jean had brought her mother into her home to care for her when mom's Alzheimer’s made it impossible for her to be alone. When the Christmas season approached, Jean realized she had to make some choices. She did not want to give up the traditions she had set with her daughters in shopping and lunches, but it wouldn’t be possible with her caregiving responsibilities. In searching for a solution, Jean visited an adult day services facility near her home. She found she could schedule the days she needed off for her mother to come in. The adult day services company also provided transportation and would pick up mom and bring her home in the evening.
Although Jean's mother was not sure she would like to go at first, she found she enjoyed the programs, meals and conversation with new friends and the activities provided.
The time it gave Jean to have for herself was worth the extra cost for the day care.
Embrace technology. Here is a solution that would have kept “Grandma” from going out in the winter cold and getting run over by a reindeer. Companies that have created monitoring systems, security alarms and other safety equipment are “tweaking” them to adapt to the needs of seniors and their care givers.

Here are a few examples:
  • Ankle or wrist bands that monitor location and alert the provider when a person has gone beyond the designated perimeter, such as out the front door of the house.
  • Motion detectors. Set throughout the home, motion detectors allow someone outside the home to follow a senior as he or she moves through the house.
  • Smart medication dispensers. Live monitoring and dispensing of pills.
  • Emergency response alert. At a touch of a button on a desktop monitor, bracelet or necklace, emergency help is summoned.
Whether providing care in your home or helping senior family members in their own homes, your use of monitoring and “tech” help aids can provide extra safety for your loved ones, and peace of mind for you.

Remember, you are not alone. Join a caregiving help group. Your local senior center may have one or go on the internet to find one. Hearing about other caregivers' problems and solutions and being able to share your own and ask questions is a great way to relieve stress and gain a new perspective. Check out websites like the National Family Caregivers Association at http://www.nfcacares.org/

Work with a Senior Care Professional. Recognize that you are doing the very best you know how. You are not a geriatric health care practitioner, geriatric care manager, home care nurse or aide, hospice provider or family mediation counselor, nor do you have the years of training and experience these professionals have, but you can definitely use their experience. In fact, using a senior care specialist will make caregiving easier for you and more beneficial for your elderly family member.
As an example:
Mark stopped by his father Dan’s home every night after work to help with any errands or things he needed around the house. He began to notice that Dan was not showering, dressing or even fixing meals some days. Another concern was his father's growing confusion and disorientation. A trip to the family doctor only brought more concern to Mark, since the doctor claimed it was just the aging process that caused the confusion.
Wanting a second professional opinion on what was best for his father, Mark hired Shelly -- a Professional Geriatric Care Manger -- to do an assessment. Shelly arranged for Mark and Dan to see a geriatrician, who advised that proper meals and an increase in some vitamins, would help clear up the confusion and disorientation. Shelly arranged for a home care company to come in daily to help with personal needs and prepare meals.
Soon Dan was back to his old self and able to function on his own.
You can find a wide variety of care professionals in your area on the National Care Planning Council website at www.longtermcarelink.net.

One more thing to remember. As a family caregiver, the greatest gift you are giving this holiday season is “Love.”

If you are a caregiver, you may want to check out Evan Farr's chapter "The Role of the Caregiver," from his popular book, The Virginia Nursing Home Survival Guide.

Image: Sura Nualpradid / FreeDigitalPhotos.net

Thursday, January 20, 2011

NFL star speaks on Alzheimer's, gets emotional

NFL Superstar Terrell Owens (T.O.) speaking on how Alzheimer's has touched his life personally.

Known for his on-the-field antics, T.O. displays a more emotional side in this clip.  "Estimates vary, but experts suggest that as many as 5.1 million Americans may have Alzheimer’s," according to the National Institute on Aging

Wednesday, January 19, 2011

Could ‘biomarkers’ be the key to predicting Alzheimer’s?

What is a biomarker??  Perhaps a useful tool to diagnose and predict dementia and cognitive decline, studies suggest. AstraZeneca defines the term as “a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention.”

Because Alzheimer’s disease is complicated to assess or diagnose, researchers have been searching for “biological clues” for years.  

A study aimed at investigating a potential relationship between “plasma beta-amyloid 42 and 42/40 levels and cognitive decline in a large group of community-dwelling older adults without dementia” adds more support for the argument that biomarkers may be a useful tool for doctors.  The biomarkers used by this study: protein framgents.

The study found that older individuals who do not suffer from dementia, but lower levels of “blood plasma and biomarkers beta-amyloid 42/40 (protein fragments),” may be at an increased risk for experiencing cognitive decline. The relationship between cognitive decline and biomarker levels was more profound among less educated participants.  

"[The use of] biomarkers to identify elderly persons at risk of developing dementia could be useful for early prevention, if and when such interventions are available, and treatment," the author of the study explained. 
The study, published in the Journal of the American Medical Association (JAMA) was reported on by Senior Journal today.  That article is available here.  

 What does this mean for the future of biomarker research? 
"Future studies should further explore the use of plasma beta-amyloid as a biomarker, assess the mechanisms by which cognitive reserve modifies this association, and determine whether increasing cognitive reserve through interventions can reduce the risk of Alzheimer disease." 
In a different study, three specific proteins in cerebrospinal fluid were found to potentially “spot” Alzheimer’s disease.  That study appeared in the Archives of Neurology.  The BusinessWeek article that reported on this study is available here.  Of note, the Senior Director of Medical and Scientific Relations at the Alzheimer’s Association had this to say:
"This just reinforces the recommendation by [Alzheimer's working groups] saying that biomarkers can actually be incorporated today into clinical practice in order to add a certain piece to the diagnosis if patients are already presenting with something that looks like Alzheimer's."
Still another study carried out by the Texas Tech University Health Sciences Center and the Texas Alzheimer’s Research Consortium, reported by Ivanhoe Newswire, found that blood serum biomarkers PLUS other clinical information could be used to more accurately classify patients with AD.  Commenting on the importance of such studies, the authors say: "There is clearly a need for reliable and valid diagnostic and prognostic biomarkers of Alzheimer's disease, and in recent years, there has been an explosive increase of effort aimed at identifying such markers."

The Texas Tech study authors appear optimistic:
"With the rapidly evolving technology and the analytic techniques available, Alzheimer's disease researchers now have the tools to simultaneously analyze exponentially more information from a host of modalities, which is likely going to be necessary to understand this very complex disease."
In other Alzheimer's related news, CNN reported that Big Pharma companies are uniting to share data:



Image: jscreationzs / FreeDigitalPhotos.net

Wednesday, December 15, 2010

Good cholesterol linked to reduced Alzheimer’s risk

Alzheimer’s disease is the 7th leading cause of death and costs about 172 billion dollars annually.[1] Due to the disease’s debilitating nature, more than 10 million caregivers of individuals with the disease are unpaid family members, friends, or volunteers. For these reasons, it is no surprise that research and medical trials are ongoing to combat the disease. Just as important as research from the scientific community, is knowledge of the steps people can take to reduce their risk for developing the disease. The December issue of Archives of Neurology reported that a high level of “good” cholesterol has been found to be linked to a reduced risk for developing Alzheimer’s.[2]

Senior Journal reported on the study from the Archives, explaining that researchers studied 1,130 healthy adults from a pool of Medicare recipients from New York, to study a possible relationship between HDL and Alzheimer’s symptoms.

While the researchers conclude that higher HDL cholesterol was associated with a lowered risk of developing Alzheimer’s disease, they also note that “[a]n important consideration in the interpretation of the results is that it was conducted an urban multiethnic elderly community with a high prevalence of risk factors for mortality and dementia.” In other words, as applied to younger individuals, the correlation between HDL and reduced risk for developing Alzheimer’s is unclear.



[1] Alz.org, Alzheimer’s Facts and Figures (2010), available at http://www.alz.org/alzheimers_disease_facts_and_figures.asp
[2] Senior Journal notes that the study was supported by the National Institute on Aging, the Charles S. Robertson Memorial Gift for Research in Alzheimer’s Disease and the Blanchette Hooker Rockefeller Foundation.

Image: Suat Eman / FreeDigitalPhotos.net